Life Style

High Consumption of Fried Food May Lead To Anxiety and Depression

We all like to eat fried food or we call it junk. Don’t we? But did you know that eating fried food can cause anxiety and depression? Isn’t it new This article talks about how eating fried food can cause psychological disorders namely anxiety and depression. 

Anxiety and Depression

Both anxiety and depression are very prominent mental health disorders. Anxiety refers to as an anticipation of future concern along with associated muscle tension and avoidance behavior.

Depression on the other hand is feeling of loneliness or hopelessness that affects the normal functioning of the individual.

Components in Fried food

Acrylamide is one of the major components in fried food which lead to toxic mode of action. In many types of research, it has been identified that when a person is exposed to acrylamide for a long time. It can cause anxiety and depression due to oxidative stress-mediated neuroinflammation. It also affects the PPAR signaling pathway and mediates acrylamide-induced lipid metabolism disorder in the brain. Through this biological convection, we can state that fried food can cause anxiety and depression.


Studies in Western countries stated that their food consumption is negatively affecting their health. Eating fried food affects our mental health. Specifically eating fried potato can cause more severe mental health problems like anxiety and depression. This phenomenon is more prominent in males and young individuals.

How fried food lead to Anxiety and depression
Biological Reasons:

Due to the presence of acrylamide in fried food worsens phototaxis and thigmotaxis and further reduces an adult zebrafish’s capacity for exploration and social interaction, exhibiting anxiety- and depressive-like behaviors. Additionally, acrylamide treatment greatly reduces the expression of the tjp2a gene, which is connected to the permeability of the blood-brain barrier. Additionally, acrylamide treatment greatly reduces the expression of the tjp2a gene, which is connected to the permeability of the blood-brain barrier. Multi-omics research revealed that acrylamide exposure over a long period of time causes changes in the brain’s lipid metabolism as well as neuroinflammation.

Zebrafish brain lipid metabolism problem caused by acrylamide is mediated by the PPAR signaling system. The development of anxiety and depressive symptoms is significantly influenced by the dysregulation of sphingolipid and phospholipid metabolism, which is specifically caused by chronic exposure to acrylamide. Acrylamide also encourages lipid peroxidation and oxidative stress, both of which contribute to cerebral neuroinflammation. Acrylamide significantly raises the lipid peroxidation indicators ()5-HETE, 11(S)-HETE, 14(S)-HDHA, indicating elevated cerebral inflammatory status. Together, these findings underscore the need of limiting fried food consumption for mental health and offer strong epidemiological and mechanistic support for unraveling the mechanism of acrylamide-triggered anxiety and depression.

Weight Gain:

Eating fried food can cause increase in weight leading to obesity causing many health problem and even causing disorder like anxiety and depression.


Fried food contains unhealthy fats which can lead to severe inflammation causing various health symptoms, which can even lead to anxiety and depression

Hence, it is important that we eat healthy food and avoid eating fried food to reduce the chance of developing psychological disorders like anxiety or depression.

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